Hyphen BioMed

Blood cancers account for about 10% of all diagnosed cancers. At the point of diagnosis, staging for exact type, location and spread of the cancer is also done. Unlike other cancer staging systems affecting organs, each type of blood cancer has its own staging criteria.

On top of that, treatments also vary from active surveillance without cancer-directed therapy to standard cancer treatments. With over 100 different types of blood cancers now recognised, it is important to have an accurate diagnosis prior to deciding on a treatment.

Videos

Flow Cytometry Workflow and Testing for Leukaemia and Lymphoma

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CPD Expert Series: Exploring Beyond CBC in Haematological Malignancies

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Detection of chromosomal translocations by Dual Fusion FISH probes on B cells lymphoma

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Applications

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A Single Tube 10-Color Flow Cytometry Assay Optimizes Detection of Minimal Residual Disease in Chronic Lymphocytic Leukemia.

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A Single Tube 10-Color Flow Cytometry Assay Optimizes Detection of Minimal Residual Disease in Chronic Lymphocytic Leukemia.

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Sartor MM, Gottlieb DJ.Sartor MM, Gottlieb DJ., Cytometry B Clinical Cytometry 2013; 84B: 96-103
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Cell Population Data–Driven Acute Promyelocytic Leukemia Flagging Through Artificial Neural Network Predictive Modeling.

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Cell Population Data–Driven Acute Promyelocytic Leukemia Flagging Through Artificial Neural Network Predictive Modeling.

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Haider, Rana Zeeshan, Ikram Uddin Ujjan, and Tahir S. Shamsi. Translational oncology 13.1 (2020): 11-16.
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Guidelines on the use of multicolour flow cytometry in the diagnosis of haematological neoplasms.

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Guidelines on the use of multicolour flow cytometry in the diagnosis of haematological neoplasms.

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Johansson U, Bloxham D, Couzens S, et al. British Committee for Standards in Haematology. Br J Haematol. 2014;165(4):455-488.
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MRD detection in multiple myeloma: comparison between MSKCC 10-color single-tube and EuroFlow 8-color 2-tube methods.

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MRD detection in multiple myeloma: comparison between MSKCC 10-color single-tube and EuroFlow 8-color 2-tube methods.

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Roshal M, Flores-Montero JA, Gao Q, et al. Blood Adv 2017; 1(12): 728-732
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Standardized flow cytometry for highly sensitive MRD measurements in B-cell acute lymphoblastic leukemia.

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Standardized flow cytometry for highly sensitive MRD measurements in B-cell acute lymphoblastic leukemia.

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Theunissen P, Mejstrikova E, Sedek L, et al. Blood. 2017;129(3):347-357.
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Use of hematopoietic progenitor cell count on the Sysmex XE-2100 for peripheral blood stem cell harvest monitoring.

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Use of hematopoietic progenitor cell count on the Sysmex XE-2100 for peripheral blood stem cell harvest monitoring.

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Letestu, Rémi, et al. Leukemia & lymphoma 48.1 (2007): 89-96.