Infection-and-Inflammation

Today, patients suffering from symptoms of infectious disease such as sepsis, flu-like illness, fever with rash, or meningitis, are typically all treated alike: By drawing samples for laboratory analysis, starting antibiotic therapy with the physician’s best guess as to the likely causes, and then hoping to learn the causative reason for the infection over a period of days from laboratory analysis.

Innovative diagnostics are required that will allow healthcare providers to distinguish, at the point of care, patients that require antibiotics and those that can be treated safely without antibiotics. In relation, this helps the rapidly growing problem of anti-microbial resistance.

Videos

Haematology Testing in the Diagnosis & Management of COVID-19 and Dengue

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Handling COVID-19 Cases – experience at a tertiary care hospital

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D-dimer, a Significant Coagulation Marker in Inflammatory and Infectious Conditions

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Beyond Routine CBC in Infection Management

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Clinical and Haematological Aspects of Dengue Infection

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Biochemistry of Infection & Inflammation in COVID-19

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An Important Update: Haemostatic Abnormalities in Covid-19 and Associated Infections

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Myths & Facts of Covid Testing

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Sysmex Joins the Fight Against AMR

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Solutions

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Clinical Utility of Immature Platelet Fraction Vol.2 Dengue

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Clinical Utility of Immature Platelet Fraction Vol.2 Dengue

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D-Dimer

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Meet-the-expert session report – Laboratory Testing for Lupus Anticoagulants

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Meet-the-expert session report – Laboratory Testing for Lupus Anticoagulants

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Reticulocyte Hemoglobin Equivalent (RET-He)

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Reticulocyte Hemoglobin Equivalent (RET-He)

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Applications

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Application of Sysmex XN-Series Automated Haematology Analyser in the Rapid Detection of Malaria

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Application of Sysmex XN-Series Automated Haematology Analyser in the Rapid Detection of Malaria

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Ningombam, A., Sarkar, A., Acharya, S. et al. Indian J Hematol Blood Transfus (2020)
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Dengue score: a proposed diagnostic predictor for pleural effusion and/or ascites in adults with dengue infection

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Dengue score: a proposed diagnostic predictor for pleural effusion and/or ascites in adults with dengue infection

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Suwarto S, Nainggolan L, Sinto R, Effendi B, Ibrahim E, Suryamin M, Sasmono RT. BMC infectious diseases. 2016 Dec;16(1):322
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Evaluation of the Sysmex UF-1000i urine flow cytometer in the diagnostic work-up of suspected urinary tract infection in a Dutch general hospital

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Evaluation of the Sysmex UF-1000i urine flow cytometer in the diagnostic work-up of suspected urinary tract infection in a Dutch general hospital

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van der Zwet WC, Hessels J, Canbolat F, Deckers MM. Clinical chemistry and laboratory medicine. 2010 Dec 1;48(12):1765-71
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Immature platelet count: a simple parameter for distinguishing thrombocytopenia in pediatric acute lymphocytic leukemia from immune thrombocytopenia

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Immature platelet count: a simple parameter for distinguishing thrombocytopenia in pediatric acute lymphocytic leukemia from immune thrombocytopenia

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Strauß, Gabriele, et al. Pediatric blood & cancer 57.4 (2011): 641-647
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Improvement in detecting sepsis using leukocyte cell population data (CPD)

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Improvement in detecting sepsis using leukocyte cell population data (CPD)

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Urrechaga E, Bóveda O, Aguirre U. Clinical Chemistry and Laboratory Medicine (CCLM). 2019 May 27;57(6):918-26
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Rapid diagnosis of uncomplicated urinary tract infection with laser flow cytometry

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Rapid diagnosis of uncomplicated urinary tract infection with laser flow cytometry

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Yang CC, Chang SJ, Shei-Dei Yang S, Lin CD, Peng CH. Urological Science. 2016 Sep 1;27(3):135-9

Applications – Covid-19

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Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy

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Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy

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Ning Tang et al. J Thromb Haemost. 2020
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Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

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Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

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Rao Guo et al.JAMA Cardiol. 2020
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

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Fei Zhou et al. Lancet. 2020 28;395(10229):1054-1062
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Critically Ill COVID-19 Infected Patients Exhibit Increased Clot Waveform Analysis Parameters Consistent with Hypercoagulability.

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Critically Ill COVID-19 Infected Patients Exhibit Increased Clot Waveform Analysis Parameters Consistent with Hypercoagulability.

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Chuen Wen Tan et al. Am J Hematol. 2020
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Diagnostic Utility of Clinical Laboratory Data Determinations for Patients with the Severe COVID-19.

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Diagnostic Utility of Clinical Laboratory Data Determinations for Patients with the Severe COVID-19.

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Yong Gao et al. J Med Virol. 2020
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ISTH interim guidance on recognition and management of coagulopathy in COVID-19

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ISTH interim guidance on recognition and management of coagulopathy in COVID-19

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Jecko Thachil et al. J Thromb Haemost. 2020
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Management of COVID‐19 Related Paediatric Blood Samples in a Clinical Haematology Laboratory

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Management of COVID‐19 Related Paediatric Blood Samples in a Clinical Haematology Laboratory

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Lam JC et al. British Journal of Haematology. 2020 doi: 10.1111/bjh.16721
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Prominent changes in blood coagulation of patients with SARS-CoV-2 infection.

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Prominent changes in blood coagulation of patients with SARS-CoV-2 infection.

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Huan Han et al. Clin Chem Lab Med. 2020
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Temporal Changes in Immune Blood Cell Parameters in COVID‐19 Infection and Recovery from Severe Infection

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Temporal Changes in Immune Blood Cell Parameters in COVID‐19 Infection and Recovery from Severe Infection

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Yip, Christina YC, et al. British Journal of Haematology. 2020 doi: 10.1111/bjh.16847