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1. Important issues in medical research started from the millennium project

This content outlines the significant issues in medical research initiated by the Millennium Project, emphasizing the contributions of Sysmex in addressing these challenges through its advanced technologies and solutions.

Important Issues in Medical Research Initiated by the Millennium Project

1. Recent advance in the diagnosis and treatment of paroxysmal nocturnal hemoglobinuria (PNH)

Discussion on the recent progress in the pathogenesis, diagnosis and treatment of Paroxysmal nocturnal hemoglobinuria (PNH).

Professor Yuzuru KANAKURA, M.D., Ph.D. The Department of Hematology and Oncology, Osaka University Graduate School of Medicine

2. Gene therapy comes of age: focusing on CAR-T cell therapy

This content outlines the significance of CAR-T cell therapy in gene therapy, highlighting the advancements in the field and emphasizing the contributions of Sysmex's technologies in supporting CAR-T cell research and clinical applications.

Gene Therapy Comes of Age: Focusing on CAR-T Cell Therapy

2. Understanding of genetic alterations in myeloproliferative neoplasms

Introduction of a research findings of JAK2V617F, CALR, and MPL mutations in patients suspected of Philadelphia-negative myeloproliferative neoplasm (MPN), as well as discussion on surrounding issues.

Professor Norio KOMATSU, M.D., Ph.D. Department of Hematology, Juntendo University School of Medicine

3. On the genetic basis of myelodysplastic syndromes

Summary of major advances of recent years in the ﬁeld of MDS research, focusing on the results of the studies by Prof. Ogawa’s team.

Professor Seishi OGAWA, M.D., Ph.D.,Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University

3. Regulatory T cell: from the past to the present

This content outlines the historical development, current advancements, and future directions of regulatory T cell research and emphasizes the role of Sysmex's technologies in supporting this innovative field.

Sysmex, a leader in healthcare technology, supports this field with advanced tools and technologies for studying and manipulating Tregs, facilitating research and clinical applications.

4. Antithrombin resistance: a new mechanism of inherited thrombophilia

Introduction of a study investigating a possible causative gene defect in the large Japanese family with inherited thrombophilia, as well as the discovery of a novel missense mutation in the prothombin gene (p.ARG596Leu) resulting in a variant prothrombin.

Professor Tetsuhito KOJIMA, M.D., Ph, D.Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine

4. Cell-based therapy for Parkinson’s disease

This content highlights the potential of cell-based therapy for Parkinson’s disease, emphasizing the role of Sysmex's technologies in supporting research and clinical applications in this innovative field.

Cell-Based Therapy for Parkinson’s Disease: Innovations and Insights from Sysmex

5. Progress and vision in the treatment of hemophilia

An overview of the recent progress and vision in the treatment of hemophilia including clinical trials on therapeutic drugs and gene therapy.

Professor Midori SHIMA, M.D., Ph, D.Department of Pediatrics, Nara Medical University

5. Retinal regenerative medicine using iPS cells

This content highlights the significance of iPS cells in retinal regenerative medicine and emphasizes the contributions of Sysmex in advancing this innovative field through its technologies and solutions.

Retinal Regenerative Medicine Using iPS Cells: Innovations and Insights from Sysmex

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1. Important issues in medical research started from the millennium project

1. Important issues in medical research started from the millennium project

1. Recent advance in the diagnosis and treatment of paroxysmal nocturnal hemoglobinuria (PNH)

1. Recent advance in the diagnosis and treatment of paroxysmal nocturnal hemoglobinuria (PNH)

2. Gene therapy comes of age: focusing on CAR-T cell therapy

2. Gene therapy comes of age: focusing on CAR-T cell therapy

2. Understanding of genetic alterations in myeloproliferative neoplasms

2. Understanding of genetic alterations in myeloproliferative neoplasms

3. On the genetic basis of myelodysplastic syndromes

3. On the genetic basis of myelodysplastic syndromes

3. Regulatory T cell: from the past to the present

3. Regulatory T cell: from the past to the present

4. Antithrombin resistance: a new mechanism of inherited thrombophilia

4. Antithrombin resistance: a new mechanism of inherited thrombophilia

4. Cell-based therapy for Parkinson’s disease

4. Cell-based therapy for Parkinson’s disease

5. Progress and vision in the treatment of hemophilia

5. Progress and vision in the treatment of hemophilia

5. Retinal regenerative medicine using iPS cells

5. Retinal regenerative medicine using iPS cells

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