Regional Viral Hepatitis Webinar 3: M2BPGi as a new biomarker in Hepatocellular Carcinoma Risk Assessment
Speaker
Assoc. Prof Dao Viet Hang, PhD, MD
Vice General Secretariat, Vietnam Association of Gastroenterology
Faculty of Internal Medicine, Hanoi Medical University
Endoscopy Centre, Hanoi Medical University Hospital
Institute of Gastroenterology and Hepatology
Moderator
Dr Jeffrey Susilo, MBBS, BMedSci
Liaison, Scientific Affairs, Sysmex Asia Pacific
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and a major health problem in Vietnam. Viral hepatitis, alcoholic hepatitis and non-alcoholic fatty liver disease are three important risk factors for HCC. In Asia Pacific region, the combination of liver ultrasound and serum alpha feto-protein (AFP) is the current method for HCC surveillance, however, its sensitivity and specificity remains low.
Mac-2-binding protein glycosylation isomer (M2BPGi) is a novel serum biomarker, which correlates with the severity of liver fibrosis. Recent studies in the literature show that it is useful in the prediction of HCC development in chronic liver disease patients. In this webinar, the M2BPGi utility in the context of HCC will be discussed, incorporating a case study to provide a clinical anecdote.