Speaker

Christina Yip, PhD

Head, NUHS Diagnostics

National University Health System Singapore

Scientific Officer

Department of Laboratory Medicine

Division of Haematology

National University Hospital Singapore

Objectives of the Lecture 

• Provide an overview of platelet function disorders
• Describe common platelet function assays
• Learn the laboratory diagnostic flow chart for the diagnosis of inherited platelet function disorders
• Review ISTH/SSC and BCSH guidelines for light transmission platelet aggregometery
• Learn about setting up platelet aggregation assay
• Discuss evaluation and reporting of platelet aggregation results
• Examine the use of other platelet parameters, including immature Platelet Fraction (IPF), platelet morphology, etc. in platelet studies
• Hear user experience with integrated platelet aggregation testing platform

Abstract: Platelets are classically known as essential cellular mediators of haemostasis and thrombosis. Qualitative and/or quantitative platelet defects may result in clinical consequences such as bleeding or thrombosis. Laboratory diagnosis of platelet disorders is an important part of haematological test service albeit, it is often limited to referral laboratories at tertiary hospitals due to its typical demand on technical expertise and expensive instrument. With the advent of technologies, there are different options of ‘simplified’ platelet function assays made available to most laboratories. In this webinar, the speaker will discuss the considerations for setting up platelet function tests at laboratories to aid in clinical management of patients with platelet-mediated diseases.

Watch Video

This video was first presented by Dr Yip at Philippines College of Haematology and Transfusion Medicine in September 2021 and broadcasted again with Sysmex on 1^st December 2021.